3D Biomatrix designs and manufactures three-dimensional scaffolds for cellular assays in drug discovery. For a diverse group of customers such as researchers and drug discovery experts, 3D Biomatrix produces high quality products that provide better outcomes. 3D Biomatrix scaffolds have been tested in bone marrow, platelets, thymus and have demonstrated positive results.

AAPharmaSyn LLC (AAP) is a global chemistry contract research organization based in Ann Arbor, Michigan. The company founded in 2006 is led by a management team with over 35 years of collective experience in the pharmaceutical industry. AAP has talented staff of former Pfizer/Parke Davis chemists with demonstrated expertise and skill in synthetic medicinal chemistry. A majority of them had worked on the Lipitor project while at Parke-Davis. As a new startup, AAPharmaSyn has achieved steady growth by providing contract medicinal chemistry research and custom synthesis services, and outsourcing services to a broad range of clients that include academic institutions, life science, pharmaceutical and biotech companies. These services include research based collaboration as well as joint application for research grants. AAPharmaSyn builds relationships with customers that focus on quality, dependable and superior service.

Formerly Global Energy Conversions, LLC, Advanced Technologies of Michigan are experts in USEPA method 24 for the estimation of VOC of paints and non-paint samples. It has also have developed unique ways to convert waste plastics to fuel and are developing ways to convert soft-shell fish casings to useful products, cleaning frying oils to extend their useful lives, conducting polymers for new lithium batteries etc.

AI Medical Devices, Inc. is a medical device company specializing in airway management.  The company has developed the Video RIFL (RIgid and Flexing Laryngoscope), an articulating video laryngoscope which improves the medical outcomes of the intubation procedure when compared to current state-of-the-art intubation equipment.

Akervall Technologies is the creator of Protech Dent products. Its thin, comfortable, pliable mouth guards can be custom fitted in minutes and offer 30% more protection than regular mouth guards. Protech Dent is ideal for sports, medical, dental and military usage.

AlphaCore Pharma LLC is developing a drug for heart attack victims that will remove the bad form of cholesterol.

As trusted technology advisors, Arivium, Inc. helps its clients make improvements in their business by offering a structured, yet flexible, approach to simplifying business practices, aligning resource goals and measures, and integrating technological advances.

ArmyProperty.com is military inventory procurement software

Audiallo is a Fabless IC analog semiconductor manufacturer bringing ultra low power analog processing to the audio space. Its Wave Signal Processor (WSP), built on technology developed at Georgia Tech consumes less than 10 μW of power and is built on reconfigurable blocks which can be rapidly adjusted to specific application needs.

AutoKnowledge is focused on meeting the internal, competitive and market information needs of automotive product developers. It provides knowledge management software applications that support competitive and benchmarking information on full vehicles and systems.

Avicenna is a spin-out from the University of Michigan. It develops and markets software applications that improve the quality of care, information flow, and financial efficiency of specialty medical clinics.

Bigwig is a simple, Excel-based planning, business development tracking, and management reporting system designed specifically for independent contractors, sole proprietors, freelancers and solo professionals.

Biopolymer Innovations is a life science company specializing in the development of biodegradable, polysaccharide-based drug delivery systems founded in 2003. The primary product under development is a drug delivery system for topical ocular drugs (glaucoma, antibacterial and anti-inflammation treatments). Biopolymer Innovations is also working in the area of tissue scaffolding for applications to support liver function.

Blaze Medical Devices, a University of Michigan spin-out, develops blood analysis devices.

Cielo MedSolutions is a leading provider of healthcare software for ambulatory care providers. Its Cielo ClinicTM enhances the quality of patient care, improves practice revenues, and optimizes practice efficiency, helping health care providers to harness the power of a preventive care and chronic disease management information system. Cielo ClinicTM is based on an all-problem, all-patient patient registry, dynamic clinical decision support and proactive population management.

CWI (Computer Works Inc) provides a broad range of computer and IT services to business and residents spanning from Downriver Detroit to Toledo, Ohio. Headquartered in Monroe, Michigan, Computer Works specializes in computer network solutions, PC repair, web development/ e-commerce and consultation. We employ the best and brightest staff to ensure solutions are developed and achieved successfully in all aspects of business.

Creative Byline, Inc. works directly with publishers to streamline the process of manuscript submission. With Creative Byline, writers can easily and affordably get their work in front of interested editors. Editors at participating publishing houses can bypass manuscript overload to spend more time on those that match what they're looking for.

CTC Holdings is commercializing advanced VOCs-to-Energy Products that convert VOC emissions into concentrated fuel.  The fuel created by CTC’s VOCs-to-Energy Products can be paired with a Stirling engine, fuel cell, IC engine or micro-turbine to create useful electricity or burned in a boiler to create thermal energy

CYJ Enterprises' first product, e-CYREN, is an emergency management system designed to help child and adult care providers quickly and effectively communicate with the families, before, during and after emergencies.

DataSpeaks Interactions® is breakthrough software to advance practical scientific understanding of complex adaptive systems such as organisms, patients, brains, and economies.

Distance Engineering provides CADKEY and Solid Edge mechanical design training CD-ROMs

EiPon Learning, LLC offers simple Web tools for language teachers. With Eipon, language teachers can record and assign speaking and pronunciation practices, conduct audio quizzes to evaluate speaking proficiency, share demonstration recordings, or offer audio feedback, all through the Web. Eipon is a toolkit for any individual who teaches or tutors a foreign language, including language teachers, tutors, and training professionals, TOEFL, TOEIC, IELTS & other standard test-preparation instructors, and speech pronunciation and accent training professionals.

EDA is focused on developing new applications based on plasma electrodymamic and electromagnetic technologies. Its principal focus is in the aerospace sector with growth opportunities now emerging in the energy and materials processing arena.

Emiliem is developing Molecular Targeted Therapeutics (MTTs) for oncology and other indications. MTTs are novel therapeutic agents that target biologically important processes central to the development and progression of cancer and other diseases.

EngXT ‘s philosophy is that simple and innovative solutions are essential for solving engineering problems efficiently, and at the lowest possible cost. We focus on developing reliable, low-cost solutions to engineering and exploration applications by leveraging on a deep understanding of science and best engineering practices. EngXT designing, manufacturing and testing facilities are located in Ann Arbor, Michigan. It benefits from research conducted at the University of Michigan and the talented workforce available in the area.

ePack helps MEMs companies bring products to market. Its solutions are built on years of intellectual property developed at the University of Michigan at Ann Arbor. The University of Michigan is one of the few places in the world that has demonstrated reliable wafer-level vacuum packaging.

Evigia is the industry-leading provider of wireless and sensing solutions. Its approach utilizes integrated sensor and ASIC technologies to improve the functionality and cost of products. These advances enhance performance, improve energy efficiency and lower the cost of asset-management throughout supply chains and sensing networks.

Fulcrum™ Composites Inc. is a technology and processing company dedicated to providing solutions to structural problems through the development and application of thermoplastic composites

Grafaktri provides extraordinary visual services for business, institutions and individuals.

GTI Risk Management is a Michigan based professional research and risk consulting firm that has been assisting the legal and business community resolve complex business, due diligence, security and liability concerns since 1962. GTI has office locations in Sault Ste. Marie, Detroit and Ann Arbor, Michigan.

Hitchsters is an easy-to-use website that conveniently connects travelers going to and from airports so that they can share a ride (and thus split the fare). The hitchsters.com matching system makes riding in a car to the airport more affordable, more convenient, safer, and more environmentally-friendly.

Humax Corporation is the pioneer in helping companies, groups, and individuals achieve measurable business results by improving their social capital. Humax was founded on research that shows people with rich social capital are better informed, more creative, more efficient, and better problem solvers. With the right networks, people save time because they know where to get the information they need.

Industrial Optical Measurement is innovating a cylinder bore probe to inspect engine blocks.

The first InnoVet ™ system manufactured in 1991 by Summit Industries was an innovative design breakthrough in veterinary radiography. Prior to this time, vets were relegated to use human medical x-ray systems for the unique needs of veterinary imaging. The InnoVet was the first x-ray system designed by veterinarians for veterinarians. This revolutionary unit combined all the tools needed for an x-ray exam: a full-size table, moveable tubestand, 300 mA generator and lead-lined cassette box into one compact package. The InnoVet product line now includes both film-based and direct digital systems, and continues the traditions of reliability and user-friendliness.

Intelligent Prosthetic Systems performs research and development of advanced prosthetic technologies to improve mobility for persons with disabilities. It works with scientists to bring the best ideas from laboratory research into commercial products that help patients. It is currently developing prosthetic feet aimed at reducing energy expenditure and improving balance during walking, as well as the systems that monitor the effectiveness of these devices during daily life

Ix Innovations is commercializing its PocketPico product. PocketPico is a portable, USB-powered picoammeter that can be used as a stand-alone instrument or connected to a PC. PocketPico streamlines the testing and measuring of very-low electrical current in chips, small circuits and materials.

We offer custom software services for small to large sized businesses. It also offers custom website design. Know Ideas specializes in open source, database driven applications and websites based on the LAMP stack (Linux, Apache, mySQL, PHP).

The Learning Bridge is a safe and fun way to complete the school day. It offers a wide range of activities – arts and crafts, homework assistance, science projects, table games, ‘virtual’ field trips, individual and team play on the playground and in the gym, dramatic play and social opportunities all on the school site.

Local Orbit, an Ann Arbor company, connects restaurants, institutions and individuals with local farmers and food producers in one convenient online location. The company is building a marketplace that combines web-based business and community building tools with the best features of farmers markets and full-service grocery stores to streamline the process of purchasing local food.

MedArray, Inc. is an emerging and dynamic membrane technology company located in Ann Arbor, committed to providing customers a unique and simple solution for their gas transfer processes.  Dedicated to manufacturing silicone hollow fibers and membrane modules containing them, MedArray currently offers its PermSelect® silicone hollow fiber membranes in three sizes: 10 centimeter square, 1,400 centimeter square, and 1.0 meter square. These modules are suitable for small-scale laboratory use to enable its customers to evaluate the membrane in their specific applications.

Mitechnews.Com is a web portal site that features stories, information and events listings about Michigan technology companies and entrepreneurs. Mitechnews.Com is owned by Michigan News Network, a corporation based in Grand Rapids, MI.

Monarch Antenna's patented Self-Structuring Antenna (SSA) improves the reliability of the wireless link. SSA responds to changes in the RF signal environment by dynamically reconfiguring its electrical shape to maximize the Signal-To-Noise-Ratio (SNR). The technology is the product of a decade of R&D effort by Delphi Corporation and Michigan State University and provides an attractive business case for adoption in machine-to-machine communication, consumer electronics and military markets.

Motor City Wipers LLC, located in Rochester Hills, is commercializing its advanced windshield wiper system that solves several of the shortcomings of today’s windshield wipers, including the build-up of snow, ice and other solid debris from the windshield wiper blade.

MySano makes Health Care Easy. Its patented technologies and database expertise help health care entities improve their consumer and provider experience by answering the above questions and more. Simple and elegant data gathering tools allow MySano to show consumer relevant detail for an entire medical staff or health care network.

NamesForLife (N4L) was developed to solve a long-standing problem in biology: resolution of the ambiguity between nomenclature and biological objects and concepts. Its architecture makes names actionable. In a N4L enabled document or database, when encountering a name, the user clicks or mouses over it and a menu of authoritative information is displayed.

New Eagle is a technology-enabled service provider located in Ypsilanti. Its MotoHawk® software fuels innovation with market leading algorithms and development methodologies that speed product commercialization.  The company is focused on the EV, hybrid power train and alternative energy markets.

NextCAT is commercializing a series of heterogenous catalysts developed by the National Biofuels Energy Lab at Wayne State University, for use in biodiesel production. These new catalysts allow producers to use less expensive raw materials in the production of biodiesel, and simplify the production process. Today, over 80% of the U.S. biodiesel producers sit idle due primarily to very high feedstock costs. With a world class team of catalysis experts, an experienced management team, and strategic partners, NextCAT will re-catalyze the biodiesel industry which will lessen our dependence on foreign oil and improve our environment.

Nico Technologies is a research and development (R&D) company located in Ann Arbor, MI, that specializes in finding practical uses for nanotechnology, particularly related to nanoscale composites for military and nanomaterials for biomedical applications. Our central corporate objective is identification and nurturing early stage technologies displaying substantial commercial potential and bringing them to the market.

Fomerly Hyrbra Drive, Limo-Reid Technologies, Inc, now NRG Dynamix, designed a variable displacement gear pump (VDGP) and motor with many applications. Simplicity of design makes it easier and less costly to manufacture and repair than vane and piston-type pumps. The relatively small size and light weight makes this pump easier to install in confined areas. For hydraulic hybrid vehicle use, the instant response of VDGP eliminates lag time and the feeling of the powertrain gradually winding-up, a phenomenon that is common in other pumps.

OcuSciences Inc. is working to develop and commercialize the OcuMet™ line of ocular metabolic imaging products. Founded by Victor Elner, M.D., Ph.D. and Howard Petty, Ph.D. at the University of Michigan’s Kellogg Eye Center, OcuSciences has innovated the retinal metabolic analysis (RMA), a novel technique that allows detection of certain eye diseases several years earlier than current clinical methods. The most significant impact of the The OcuMet™ products on current healthcare practice is in the early detection and monitoring of diabetes. Once diagnosed with disease, OcuMet™ helps monitor disease progression and mitigation by treatment.

Opteos provides customers with unique RF characterization solutions based on electro-optic and magneto-optic sensing technologies, by both offering customized measurement services and introducing industry-grade instrumentation products. Use of Opteos services and instruments can lead to a significant reduction in product-development time and cost, as well as more comprehensive and effective evaluations of microwave systems - crucial factors in a dynamic, competitive environment.

Phrixus Pharmaceuticals was created to develop and commercialize Carmeseal™, a novel therapy for the treatment of heart failure in the general population and in patients with Duchenne Muscular Dystrophy.

Planomatic is an online tool for Realtors. It creates vibrant 3-D floor plans enriched with elegant professional photos. It’s a stunning interactive experience that delivers what buyers need and sellers demand.

Based in Chicago, Product Animations, Inc (PAI) uses its proprietary software to efficiently convert standard operating procedures, 3D models and animations into powerful, yet affordable, virtual machine simulations for training new operators on complicated manufacturing equipment, training experienced operators on infrequent tasks and providing operators with line-side visual reference tools to support operations.

Quantum Signal (QS) is an engineering research and development firm specializing in advanced image processing and interactive simulation. QS develops software solutions for its commercial and government customers, in fields ranging from mobile robotics to forensics to video games, and more!

Part of Summer 2012 Internship Program, posted by M Salley

Red Cedar Technology accelerates the engineering design process with the world’s fastest, most comprehensive optimization software. Powerful, yet intuitive to use, HEEDS® Professional interfaces with all popular CAE applications to automate and expedite the design process.

The first SensiTile was created to translate poetic ideas into material form. This led not only to the discovery of new aesthetic phenomena, but also to a whole new set of fabrication techniques and processes to create the SensiTile quality in different materials.

Shepherd Intelligent Systems (SIS), a University of Michigan spin out, provides easily accessible, reliable, real-time vehicle location information directly to the passengers and managers of public transit. SIS’s proprietary predictive algorithms incorporate parameters such as day, date, time, temperature and historical travel time to accurately forecast arrival times of fixed route and non-route-based vehicles.

Solarflex is commercializing organic solar cells.  Solarflex’s cells offer greater efficiency and lower cost compared to other solar cells currently on the market.   

Based in the Chicago area, Surgimatix is a privately held company that develops innovative surgical devices. Its product development efforts are the result of close collaboration between experienced engineers and surgeons. The mission of the company is to commercialize products that improve clinical outcomes while increasing efficiency, patient comfort, and safety.

The Whole Brain Group, LLC, based in Ann Arbor, offers AccreditStation to helps educational institutions, community hospitals, healthcare systems, and VA facilities manage successful AAHRPP accreditation projects. In addition to web applications, the company offers web design, social media coaching and training, and mobile application development.

ToolWorx is a systems integrator specializing in automated data collection applications for lot/part traceability and error proofing. Its unique ToolWorx Bridge™ can provide an unparalleled level of scalability to meet today's ever changing business needs. It provides customers with customized data collection solutions, not short-lived custom written applications.

Ultrasound Medical Devices develops advanced algorithms and software for enhanced cardiac ultrasound medical imaging. The company specialized in imaging and advanced sensor technology.

Vestaron Corporation is developing a new generation of insecticides by employing peptides sourced from spiders – insecticides that are ideally suited for the environmentally conscious, twenty-first century. Over 50 unique, spider-venom peptides with novel sites of action have been identified and are being exploited. This patented technology is exclusively licensed to Vestaron

Virtaul Space Design is developing an omni-directional treadmill for use in virtual reality, fitness and other physical demands.

White Pine Systems, LLC, a Michigan-based company formed in 2006, has created SPINN, the Secure Personal Information and Notification Network. SPINN offers Internet-based Personal Health Applications that support the Patient-Centered Medical Home. These solutions improve care coordination between healthcare providers, patients and their families to prevent avoidable hospitalizations, reduce emergency room visits, and control drug costs thereby reducing total cost and improving the quality of care.